This is typically due to Word within the Cloud Environment being unable to read this new document and causing Word to stop responding which will pause your Profile session as Profile will be waiting on a reply from Word.
The first step is to notify Profile Support by raising a new online case as they will be able to remove the new document from the back end of Profile (as you cannot delete the document from within Profile due to the session freezing) and get the record working again.
The Support agent can either remove or recover the document, this would be up to yourself dependent if you have a copy. Once you have the original document, proceed to copy all of the contents from the document and paste this into a new Notepad document. As Notepad does not support any formatting or special characters, this will strip any characters that Word was originally unable to process.
Last step is to copy the contents back from Notepad and paste into a new Word Document and upload this new Word Document into Profile. The record should have no more issues loading up anymore.